Decreasing case fatality rate following invasive pneumococcal disease, North East England, 2006–2016
نویسندگان
چکیده
منابع مشابه
Increased Invasive Pneumococcal Disease, North East England, UK
Since April 2014, invasive pneumococcal disease incidence has increased substantially across North East England, United Kingdom, reversing the decline that followed the 2006 introduction of pneumococcal conjugate vaccines. Significant increases occurred in 23-valent polysaccharide vaccine serotypes and nonvaccine serotypes. Trends in other regions and long-term effects of multivalent vaccines r...
متن کاملInvasive pneumococcal disease and socioeconomic deprivation: a population study from the North East of England.
BACKGROUND Some communicable diseases disproportionately affect poor and vulnerable groups. Invasive pneumococcal disease (IPD) is an important cause of morbidity and mortality; however, the relationship between IPD and deprivation has not been well described. METHODS Population based study assessing the relationship between incidence of IPD and deprivation in the North East of England using ...
متن کاملEpidemiology of invasive pneumococcal infections: manifestations, incidence and case fatality rate correlated to age, gender and risk factors
BACKGROUND Incidence, manifestations and case-fatality rate (CFR) of invasive pneumococcal disease (IPD) vary with age and comorbidities. New vaccines, changing age distribution, prolonged survival among immunocompromised patients and improved sepsis management have created a need for an update of basic facts to inform vaccine recommendations. METHODS Age, gender and comorbidities were relate...
متن کاملInvasive Pneumococcal Disease after Routine Pneumococcal Conjugate Vaccination in Children, England and Wales
We assessed known risk factors, clinical presentation, and outcome of invasive pneumococcal disease (IPD) in children 3-59 months of age after introduction of the 7-valent pneumococcal conjugate vaccine (PCV7) in England and Wales. During September 2006-March 2010, a total of 1,342 IPD episodes occurred in 1,332 children; 14.9% (198/1,332) had comorbidities. Compared with IPD caused by PCV7 ser...
متن کاملInvasive pneumococcal disease.
INTRODUCTION Streptococcus pneumoniae, the pneumococcus, is a Gram-positive diplococcus with more than 90 serotypes determined by the polysaccharide composition of its capsule. It is carried asymptomatically in approximately 50% of people.1 It can cause both non-invasive and invasive disease. Invasive pneumococcal disease (IPD) refers to disease in which the bacterium enters a sterile site such...
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ژورنال
عنوان ژورنال: Epidemiology and Infection
سال: 2019
ISSN: 0950-2688,1469-4409
DOI: 10.1017/s0950268819000657